Throughout his career, Lee has focused on transforming new or under-performing businesses into profitable endeavors. In 2000, he helped develop the user experience for the original start-up Art.com. From there, Lee worked on a number of eCommerce sites, including Medical Arts Press (Staples), growing sales to $130 million. In 2009, Lee took on a new project when asked by Medline Industries to build a platform that would offer continuing education for clinicians. He developed MedlineUniversity.com. Today, over 85,000 courses are successfully completed each month, and Medline University has a library of over 300 courses, many incorporating interactive and gaming elements.